ObaCell® Obesity-on-a-Chip

ObaCell® Obesity-on-a-Chip is a next-generation advancement for researchers seeking to redefine drug discovery in metabolic diseases. This innovative platform offers an unparalleled opportunity to emulate the intricate physiology of an obese individual in a fraction of the time, accelerating the pace of research and enabling swift identification of promising drug candidates.

Key Features & Applications:

• 3D Cellular System: Human adipose-derived stromal/stem cells differentiated into adipocytes with large lipid droplets, offering a metabolically active adipose model responsive to GLP-1 drugs.

• Adipocyte Hypertrophy Simulation: Increased lipid size mimics adipocyte hypertrophy, providing a more accurate representation of obese physiology. Model also simulates fasting/feeding.

• Enhanced Metabolic Function: Replicates human adipose tissue metabolism, facilitating precise drug screening and research.

• Dynamic Compatibility: Highly compatible with functional assays and dynamic outputs, ensuring reliable and reproducible experimental results.

• Customizable: Allows for selection of unique cell donors from our diverse inventory to match the prevalent population modeled in your study

Endpoint Services:

• Lipid Droplet Quantification

• Metabolic Activity

• Cytotoxicity & Viability Staining

• Secretome Analysis

• Cytokine Profiles

• RNA And Protein Expression

• Lipolysis

• Glucose Uptake

• Microscopy

• Bright-field

• Fluorescent

• Confocal

• High-throughput