ObaCell® ASC Fat-on-a-Chip Live Plate

ObaCell® was created as a tool for disease modeling and drug screening; moreover, it's a versatile plug-and-play system capable of seamless integration with other organ-on-a-chip models, offering boundless potential for transformative research and innovation.

ObaCell® ASC Fat-on-a-Chip Live Plate is a ready to use functional adipose organoid model provided to you in a 96-well plate format. Customize your model by choosing a unique cell donor(s) from our diverse inventory that best represents the prevalent population modeled in your study. Choose up to 4 cell donors per plate. A 3-week lead time is needed to initiate culture in our lab before delivering to you.

Endpoint analyses capable of this model include, but are not limited to, brightfield and fluorescent imaging, confocal microscopy, high-throughput microscopy, cell viability staining, metabolic activity assays via alamarblue or similar reagents, cell retrieval, histological staining, secretome analysis, cytokine profiles, and RNA and protein expression.

Model Highlights

• In-vitro self-assembled organoids
• Physiologically and functionally relevant human-derived adipose model
• Matrix protein profile supports cell growth, motility, and vascular response

Product Components

1 ready to use 3D adipose organoid model in a 96-well plate format.

• 92 tests

Consists of ASC embedded in our ObaGel® + ObaVate hydrogel scaffold and differentiated into pre-adipocytes for 2 weeks.

Product Formats

We suggest choosing a donor pool for pilot studies to lower variability of donor performance. Priced as 1 cell donor.

Companion Products

StromaQual3D Maintenance Media

AdipoQual3D Adipogenic Differentiation Media

ObaZolve Cell Retrieval Agent

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Relevant Publications

2021

• Human Adipose-Derived Stromal/Stem Cell Culture and Analysis Methods for Adipose Tissue Modeling In Vitro: A Systematic Review. Cells. 2021 Jun 3; 10(6):1378

2020

• Human Adipose Derived Cells in Two- And Three-Dimensional Cultures: Functional Validation of an In Vitro Fat Construct. Stem Cells Int. 2020 Jun 10
• Fat-on-a-Chip Models for Research and Discovery in Obesity and Its Metabolic Co-Morbidities Tissue Eng Part B Rev. 2020 Mar 26.